Within the last few hours, three men were killed by gunmen in the McCooks Pen community. One person was killed in Waterford.
There were also reports of a shoot-out between gunmen and police in the March Pen Road area of Spanish Town.
The incidents are the latest in a string of murders and fire-bombings which are being carried out in St Catherine.
The three men killed today have been identified as Peter McBean, 39; Dwayne Murray, 23 and Robert Sankey, 26. A 14-year-old has been shot an injured. His condition is uncertain.
The men were all at a bar in McCooks Pen when gunmen in a white car opened fire hitting them, before fleeing.
Murders have also been reported in Braeton, Waterford, and Newlands in Portmore.